CRA II

CRA II/Senior CRA - Early Phase

ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines and treatments to patients faster.

As a values-driven organisation, integrity, collaboration, agility, and inclusion are at the heart of how we work and interact with each other, customers, patients and suppliers.

As a CRA II or Senior CRA within our Early Phase team, you'll play a critical role in studies that sit at the very beginning of the drug development journey, including first-in-human and proof-of-concept research. Working alongside leading investigators, sponsors, and specialist clinical teams, you'll help advance promising new therapies from concept to clinical reality.

Unlike traditional large-scale monitoring roles, you'll focus on a smaller portfolio of approximately 3-4 sites across the UK, enabling you to build strong site relationships, maintain exceptional quality oversight, and make a genuine impact on the success of each study.

What You'll Be Doing

• Managing site qualification, initiation, monitoring and close-out activities across a portfolio of UK Early Phase studies.
• Building strong partnerships with investigators and site teams to ensure study success.
• Ensuring patient safety, protocol compliance, and data integrity throughout the clinical trial lifecycle.
• Reviewing study data, resolving site queries, and proactively identifying and mitigating risks.
• Supporting sponsors and project teams through the unique operational challenges associated with early development programmes.
• Acting as a trusted clinical research expert, providing guidance and support to sites and internal stakeholders.

What We're Looking For

• CRA II: Previous independent monitoring experience across clinical trials.
• Senior CRA: Significant independent monitoring experience with the ability to manage complex studies and act as a mentor for less experienced colleagues.
• Strong understanding of ICH-GCP, regulatory requirements, and clinical trial operations.
• Excellent relationship-building and communication skills.
• Ability to work proactively, independently, and collaboratively within a global study team.
• Life Science, Nursing, Pharmacy, or other relevant healthcare degree (or equivalent experience).
• Able to travel across the UK as required to complete onsite visits
• Employment with ICON is contingent upon having the legal right to work in the country where the role is based.

Rewards & Benefits

• ICON offers a competitive and comprehensive total rewards package designed to support your health, wellbeing, and career development.
• Benefits may include: Competitive base salary and performance related incentives
• Health and wellbeing programmes including medical, dental, and vision coverage where applicable

Retirement and pension plans

• Life assurance and disability coverage
• Employee assistance programmes and wellbeing resources
• Learning and development opportunities through structured training and career pathways
• Benefits may vary depending on role and location.
• Visit our careers site to read more about the benefits ICON offers.

Inclusion and Accessibility

• ICON is an equal opportunity employer. We are committed to building an inclusive and accessible workplace where everyone feels valued and supported.
• If you require reasonable accommodations during the recruitment process, please let us know or submit a request here
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• Are you a current ICON Employee? Please click here to apply