About the role
Research Associate I, Pharmaceutical Development ~ Contract
- Nurix Therapeutics is a biopharmaceutical company focused on the discovery, development, and
- commercialization of small molecule therapies designed to modulate cellular protein levels as a novel
- treatment approach for cancer and immune disorders. Leveraging Nurix’s extensive expertise in E3
- ligases together with its proprietary DNA-encoded libraries, Nurix has built DELigase, an integrated
- discovery platform to identify and advance novel drug candidates targeting E3 ligases, a broad class of
- enzymes that can modulate proteins within the cell. Nurix’s drug discovery approach is to either harness
- or inhibit the natural function of E3 ligases within the ubiquitin proteasome system to selectively
- decrease or increase cellular protein levels.
Description
- Nurix is looking for a Research Associate I, Pharmaceutical Development to provide scientific, technical,
- and hands-on support of drug discovery and product development related to small molecules from early
- discovery to clinical trial enabling studies.
- Prepare and characterize preclinical formulations in support of multiple programs.
- Perform stability and solubility testing using HPLC/UPLC.
- Assist with pre-formulation and formulation development for oral solid dosage forms.
- Contribute to internal and external presentations and publications.
Qualifications
- Thorough understanding of basic chemistry principles
- Excellent basic quantitative laboratory skills including weighing, pipetting, and use of volumetric
glassware
- Strong basic HPLC/UPLC skills and understanding (XRD and Mass Spec experience a plus)
- Excellent organizational and documentation skills
- Proficiency in Microsoft 365
- Experience in safe handling of potent compounds
- BS/BA or higher in chemistry, pharmaceutics, engineering, or related field with 2 - 4 years of industry experience
Salary Range: 40/hr - 55/hr
Location: Brisbane, CA - Onsite